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Real-time detection reveals that effectors couple dynamin's GTP-dependent conformational changes to the membrane

The GTPase dynamin is a mechanochemical enzyme involved in membrane fission, but the molecular nature of its membrane interactions and their regulation by guanine nucleotides and protein effectors remain poorly characterized. Using site-directed fluorescence labeling and several independent fluoresc...

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Detalhes bibliográficos
Main Authors: Ramachandran, Rajesh, Schmid, Sandra L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206142/
https://ncbi.nlm.nih.gov/pubmed/18079695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601961
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