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Dynamin-catalyzed membrane fission requires coordinated GTP hydrolysis.

Dynamin is the most-studied membrane fission machinery and has served as a paradigm for studies of other fission GTPases; however, several critical questions regarding its function remain unresolved. In particular, because most dynamin GTPase domain mutants studied to date equally impair both basal...

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Autors principals: Ya-Wen Liu, Juha-Pekka Mattila, Sandra L Schmid
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2013-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3561337?pdf=render
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