Dynamic clustering of dynamin-amphiphysin helices regulates membrane constriction and fission coupled with GTP hydrolysis

Dynamin is a mechanochemical GTPase essential for membrane fission during clathrin-mediated endocytosis. Dynamin forms helical complexes at the neck of clathrin-coated pits and their structural changes coupled with GTP hydrolysis drive membrane fission. Dynamin and its binding protein amphiphysin co...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Takeda, Tetsuya, Kozai, Toshiya, Yang, Huiran, Ishikuro, Daiki, Seyama, Kaho, Kumagai, Yusuke, Abe, Tadashi, Yamada, Hiroshi, Uchihashi, Takayuki, Ando, Toshio, Takei, Kohji
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Structural Biology and Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780043/
https://ncbi.nlm.nih.gov/pubmed/29357276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30246
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