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cin-4, a Gene With Homology to Topoisomerase II, Is Required for Centromere Resolution by Cohesin Removal From Sister Kinetochores During Mitosis

The back-to-back geometry of sister kinetochores is essential in preventing loss or damage of chromosomes during mitosis. Kinetochore orientation is generated in part by a process of resolving kinetochores at the centromere (centromere resolution) prior to spindle interactions. Because few of the ge...

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Detalles Bibliográficos
Main Authors: Stanvitch, Gerald, Moore, Landon L.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206113/
https://ncbi.nlm.nih.gov/pubmed/18202360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.075275
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