A comparative study of the central effects of specific POMC-derived melanocortin peptides on food intake and body weight in Pomc null mice

Functional disruption of either MC3R or MC4R results in obesity, implicating both in the control of energy homeostasis. The ligands for these receptors are derived from the prohormone POMC, which is post-translationally processed to produce a set of melanocortin peptides with a range of activities a...

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Auteurs principaux: Tung, YC Loraine, Piper, Sarah J, Yeung, Debra, O’Rahilly, Stephen, Coll, Anthony P
Format: Artigo
Langue:Inglês
Publié: 2006
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2204083/
https://ncbi.nlm.nih.gov/pubmed/16959830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2006-0866
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