Llwytho...
Altered Functional Expression of Purkinje Cell Calcium Channels Precedes Motor Dysfunction in Tottering Mice
In tottering mice, a point mutation in the gene encoding P-type (Ca(v)2.1) voltage-gated calcium channels results in ataxia, absence epilepsy, and motor dystonia that appear 3–4 weeks postnatal. The aberrant motor behaviors have been linked to cerebellar dysfunction, and adult Purkinje cells (PCs) o...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2007
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2203215/ https://ncbi.nlm.nih.gov/pubmed/18023294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.09.052 |
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