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Motor Dysfunction and Altered Synaptic Transmission at the Parallel Fiber-Purkinje Cell Synapse in Mice Lacking Potassium Channels Kv3.1 and Kv3.3
Micelacking both Kv3.1 and both Kv3.3 K(+) channel alleles display severe motor deficits such as tremor, myoclonus, and ataxic gait. Micelacking one to three alleles at the Kv3.1 and Kv3.3 loci exhibit in an allele dose-dependent manner a modest degree of ataxia. Cerebellar granule cells coexpress K...
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| Yayımlandı: | J Neurosci |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Society for Neuroscience
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6740750/ https://ncbi.nlm.nih.gov/pubmed/12930807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-20-07677.2003 |
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