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Potassium Channel Blockers Inhibit the Triggers of Attacks in the Calcium Channel Mouse Mutant tottering

Humans with the disorder episodic ataxia type 2 (EA2) and the tottering mouse mutant exhibit episodic attacks induced by emotional and chemical stress. Both the human and mouse disorders result from mutations in CACNA1A, the gene encoding the α(1)2.1 subunit of Ca(v)2.1 voltage-gated calcium channel...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Weisz, Catherine J. C., Raike, Robert S., Soria-Jasso, Luis E., Hess, Ellen J.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724952/
https://ncbi.nlm.nih.gov/pubmed/15843617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0098-05.2005
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