The BH3-only protein Puma plays an essential role in cytokine deprivation–induced apoptosis of mast cells

Mast cells play critical roles in the regulation of inflammation. One characteristic feature of mast cells is their relatively long lifespan in vivo. Members of the Bcl-2 protein family are regulators of cell survival and apoptosis, where the BH3-only proteins are critical proapoptotic proteins. In...

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Bibliographische Detailangaben
Hauptverfasser: Ekoff, Maria, Kaufmann, Thomas, Engström, Maria, Motoyama, Noboru, Villunger, Andreas, Jönsson, Jan-Ingvar, Strasser, Andreas, Nilsson, Gunnar
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2007
Schlagworte:
Immunobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200922/
https://ncbi.nlm.nih.gov/pubmed/17634411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-02-073957
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