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Mutational analysis of S12 protein and implications for the accuracy of decoding by the ribosome
The fidelity of aminoacyl-tRNA selection by the ribosome depends on a conformational switch in the decoding center of the small ribosomal subunit induced by cognate but not by near-cognate aminoacyl tRNA. The aminoglycosides paromomycin and streptomycin bind to the decoding center and induce related...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200631/ https://ncbi.nlm.nih.gov/pubmed/17967466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.10.003 |
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