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Thyroid peroxidase autoantibody epitopic ‘fingerprints’ in juvenile Hashimoto's thyroiditis: evidence for conservation over time and in families

In Hashimoto's thyroiditis, the humoral component is manifest by autoantibodies to thyroid peroxidase (TPO). Epitopic ‘fingerprinting’ of polyclonal serum TPO autoantibodies has been facilitated by the molecular cloning and expression as Fab of a repertoire of human TPO autoantibody genes. To i...

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Dettagli Bibliografici
Autori principali: JAUME, J C, BUREK, C L, HOFFMAN, W H, ROSE, N R, MCLACHLAN, S M, RAPOPORT, B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200393/
https://ncbi.nlm.nih.gov/pubmed/8603516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.d01-659.x
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