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Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia
SV-40 T antigen (TAg), human K-rasVal12, and a dominant negative mutant of human p53 (p53Ala143) have been expressed singly and in all possible combinations in postmitotic enterocytes distributed throughout the duodenal-colonic axis of 1-12-mo-old FVB/N transgenic mice to assess the susceptibility o...
Guardat en:
| Format: | Artigo |
|---|---|
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200156/ https://ncbi.nlm.nih.gov/pubmed/8227147 |
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