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Beyond the monoaminergic hypothesis: neuroplasticity and epigenetic changes in a transgenic mouse model of depression

The monoamine hypothesis of depression has dominated our understanding of both the pathophysiology of depression and the action of pharmacological treatments for the last decades, and it has led to the production of several generations of antidepressant agents. However, there are serious limitations...

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Detalhes bibliográficos
Main Authors: Massart, Renaud, Mongeau, Raymond, Lanfumey, Laurence
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405682/
https://ncbi.nlm.nih.gov/pubmed/22826347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0212
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