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Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons
Amyloid beta-protein (A beta), the principal constituent of senile plaques seen in Alzheimer's disease (AD), is derived by proteolysis from the beta-amyloid precursor protein (beta PP). The mechanism of A beta production in neurons, which are hypothesized to be a rich source of A beta in brain,...
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| Formato: | Artigo |
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| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1995
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2199904/ https://ncbi.nlm.nih.gov/pubmed/7721945 |
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