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Enhanced angiotensin converting enzyme 2 regulates the insulin/Akt signalling pathway by blockade of macrophage migration inhibitory factor expression

BACKGROUND AND PURPOSE: Macrophage migration inhibitory factor (MIF) is now known to be a pro-inflammatory cytokine associated with insulin resistance. Our aim was to investigate whether angiotensin converting enzyme 2 (ACE2) could modulate the expression of MIF and the insulin/Akt-endothelial nitri...

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Detalhes bibliográficos
Main Authors: Zhong, J-C, Yu, X-Y, Lin, Q-X, Li, X-H, Huang, X-Z, Xiao, D-Z, Lin, S-G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199394/
https://ncbi.nlm.nih.gov/pubmed/17906677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707482
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