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The use of the Chandler loop to examine the interaction potential of NXY-059 on the thrombolytic properties of rtPA on human thrombi in vitro

BACKGROUND AND PURPOSE: Recombinant tissue-type plasminogen activator (rtPA) is the only globally approved treatment for acute ischaemic stroke. Other potential treatments might be administered with rtPA, making it important to discover whether compounds interfere with rtPA-induced lysis. We evaluat...

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Autors principals: Mutch, N J, Moore, N R, Mattsson, C, Jonasson, H, Green, A R, Booth, N A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199381/
https://ncbi.nlm.nih.gov/pubmed/17982476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707543
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