The use of the Chandler loop to examine the interaction potential of NXY-059 on the thrombolytic properties of rtPA on human thrombi in vitro

BACKGROUND AND PURPOSE: Recombinant tissue-type plasminogen activator (rtPA) is the only globally approved treatment for acute ischaemic stroke. Other potential treatments might be administered with rtPA, making it important to discover whether compounds interfere with rtPA-induced lysis. We evaluat...

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Autori principali: Mutch, N J, Moore, N R, Mattsson, C, Jonasson, H, Green, A R, Booth, N A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199381/
https://ncbi.nlm.nih.gov/pubmed/17982476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707543
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