PI-3K/Akt Pathway-Dependent Cyclin D1 Expression Is Responsible for Arsenite-Induced Human Keratinocyte Transformation

BACKGROUND: Long-term exposure of arsenite leads to human skin cancer. However, the exact mechanisms of arsenite-induced human skin carcinogenesis remain to be defined. OBJECTIVES: In this study, we investigated the potential role of PI-3K/Akt/cyclin D1in the transformation of human keratinocytic ce...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Ouyang, Weiming, Luo, Wenjing, Zhang, Dongyun, Jian, Jinlong, Ma, Qian, Li, Jingxia, Shi, Xianglin, Chen, Jingyuan, Gao, Jimin, Huang, Chuanshu
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Institute of Environmental Health Sciences 2008
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199295/
https://ncbi.nlm.nih.gov/pubmed/18197291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.10403
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge