PI3K/Akt/JNK/c-Jun Signaling Pathway is a Mediator for Arsenite-Induced Cyclin D1 Expression and Cell Growth in Human Bronchial Epithelial Cells

Arsenite exposure is associated with an increased risk of human lung cancer. However, the molecular mechanisms underlying the arsenite-induced human lung carcinogenesis remain elusive. In this study, we demonstrated that arsenite upregulates cyclin D1 expression/activity to promote the growth of hum...

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Autores principales: Ding, Jin, Ning, Beifang, Huang, Yi, Zhang, Dongyun, Li, Jingxia, Chen, Chang-Yan, Huang, Chuanshu
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758122/
https://ncbi.nlm.nih.gov/pubmed/19519318
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