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Correction of fragile X syndrome in mice

Fragile X syndrome (FXS) is the most common form of heritable mental retardation and the leading identified cause of autism. FXS is caused by transcriptional silencing of the FMR1 gene that encodes the fragile X mental retardation protein (FMRP), but the pathogenesis of the disease is unknown. Accor...

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Detalhes bibliográficos
Main Authors: Dölen, Gül, Osterweil, Emily, Shankaranarayana Rao, B. S., Smith, Gordon B., Auerbach, Benjamin D., Chattarji, Sumantra, Bear, Mark F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199268/
https://ncbi.nlm.nih.gov/pubmed/18093519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.12.001
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