Correction of fragile X syndrome in mice

Fragile X syndrome (FXS) is the most common form of heritable mental retardation and the leading identified cause of autism. FXS is caused by transcriptional silencing of the FMR1 gene that encodes the fragile X mental retardation protein (FMRP), but the pathogenesis of the disease is unknown. Accor...

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Bibliographic Details
Main Authors: Dölen, Gül, Osterweil, Emily, Shankaranarayana Rao, B. S., Smith, Gordon B., Auerbach, Benjamin D., Chattarji, Sumantra, Bear, Mark F.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199268/
https://ncbi.nlm.nih.gov/pubmed/18093519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.12.001
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