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Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice
Fragile X syndrome (FXS), the most commonly inherited form of mental retardation and autism, is caused by transcriptional silencing of the fragile X mental retardation 1 (FMR1) gene and consequent loss of the fragile X mental retardation protein. Despite growing evidence suggesting a role of specifi...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1899186/ https://ncbi.nlm.nih.gov/pubmed/17592139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705003104 |
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