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Specific SHP-2 partitioning in raft domains triggers integrin-mediated signaling via Rho activation
Cell signaling does not occur randomly over the cell surface, but is integrated within cholesterol-enriched membrane domains, termed rafts. By targeting SHP-2 to raft domains or to a non-raft plasma membrane fraction, we studied the functional role of rafts in signaling. Serum-depleted, nonattached...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2199243/ https://ncbi.nlm.nih.gov/pubmed/11956229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200109031 |
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