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Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization

Redistribution of specialized molecules in migrating cells develops asymmetry between two opposite cell poles, the leading edge and the uropod. We show that acquisition of a motile phenotype in T lymphocytes results in the asymmetric redistribution of ganglioside GM3- and GM1-enriched raft domains t...

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Detalhes bibliográficos
Main Authors: Gómez-Moutón, Concepción, Abad, Jose Luis, Mira, Emilia, Lacalle, Rosa Ana, Gallardo, Eduard, Jiménez-Baranda, Sonia, Illa, Isabel, Bernad, Antonio, Mañes, Santos, Martínez-A., Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55505/
https://ncbi.nlm.nih.gov/pubmed/11493690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171160298
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