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Mutations in the Human λ5/14.1 Gene Result in B Cell Deficiency and Agammaglobulinemia

B cell precursors transiently express a pre–B cell receptor complex consisting of a rearranged mu heavy chain, a surrogate light chain composed of λ5/14.1 and VpreB, and the immunoglobulin (Ig)-associated signal transducing chains, Igα and Igβ. Mutations in the mu heavy chain are associated with a c...

詳細記述

保存先:
書誌詳細
主要な著者: Minegishi, Yoshiyuki, Coustan-Smith, Elaine, Wang, Yui-Hsi, Cooper, Max D., Campana, Dario, Conley, Mary Ellen
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199185/
https://ncbi.nlm.nih.gov/pubmed/9419212
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