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Novel mechanisms control the folding and assembly of λ5/14.1 and VpreB to produce an intact surrogate light chain

Surrogate light chain, which escorts the mu heavy chain to the cell surface, is a critical component of the pre-B cell receptor complex. The two proteins that comprise the surrogate light chain, VpreB and λ5/14.1, contain both unique regions and Ig-like domains. The unique regions have been postulat...

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Detalhes bibliográficos
Main Authors: Minegishi, Yoshiyuki, Hendershot, Linda M., Conley, Mary Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15891/
https://ncbi.nlm.nih.gov/pubmed/10077633
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