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The pre-B-cell receptor induces silencing of VpreB and λ5 transcription
The pre-B-cell receptor (pre-BCR), composed of Ig heavy and surrogate light chain (SLC), signals pre-BII-cell proliferative expansion. We have investigated whether the pre-BCR also signals downregulation of the SLC genes (VpreB and λ5), thereby limiting this expansion. We demonstrate that, as BM cel...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2005
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283949/ https://ncbi.nlm.nih.gov/pubmed/16281060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600850 |
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