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Immunoproteasome Assembly: Cooperative Incorporation of Interferon γ (IFN-γ)–inducible Subunits

LMP2, LMP7, and MECL are interferon γ–inducible catalytic subunits of vertebrate 20S proteasomes, which can replace constitutive catalytic subunits (delta, X, and Z, respectively) during proteasome biogenesis. We demonstrate that MECL requires LMP2 for efficient incorporation into preproteasomes, an...

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Detalhes bibliográficos
Main Authors: Griffin, Thomas A., Nandi, Dipankar, Cruz, Miguel, Fehling, Hans Jörg, Kaer, Luc Van, Monaco, John J., Colbert, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199179/
https://ncbi.nlm.nih.gov/pubmed/9419215
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