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CD19-Regulated Signaling Thresholds Control Peripheral Tolerance and Autoantibody Production in B Lymphocytes

The CD19 cell surface molecule regulates signal transduction events critical for B lymphocyte development and humoral immunity. Increasing the density of CD19 expression renders B lymphocytes hyper-responsive to transmembrane signals, and transgenic mice that overexpress CD19 have increased levels o...

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Detalhes bibliográficos
Main Authors: Inaoki, Makoto, Sato, Shinichi, Weintraub, Bennett C., Goodnow, Christopher C., Tedder, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199156/
https://ncbi.nlm.nih.gov/pubmed/9382890
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