A Study of the Interferon Antiviral Mechanism: Apoptosis Activation by the 2–5A System

The 2–5A system contributes to the antiviral effect of interferons through the synthesis of 2–5A and its activation of the ribonuclease, RNase L. RNase L degrades viral and cellular RNA after activation by unique, 2′–5′ phosphodiester-linked, oligoadenylates [2–5A, (pp)p5′ A2′(P5′A2′)](n), n ⩾2. Bec...

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Bibliographische Detailangaben
Hauptverfasser: Castelli, JoAnn C., Hassel, Bret A., Wood, Katherine A., Li, Xiao-Ling, Amemiya, Kei, Dalakas, Marinos C., Torrence, Paul F., Youle, Richard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1997
Schlagworte:
Brief Definitive Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199051/
https://ncbi.nlm.nih.gov/pubmed/9294150
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