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RNase L Mediates the Antiviral Effect of Interferon through a Selective Reduction in Viral RNA during Encephalomyocarditis Virus Infection

The 2′,5′-oligoadenylate (2-5A) system is an RNA degradation pathway which plays an important role in the antipicornavirus effects of interferon (IFN). RNase L, the terminal component of the 2-5A system, is thought to mediate this antiviral activity through the degradation of viral RNA; however, the...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Li, Xiao-Ling, Blackford, John A., Hassel, Bret A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1998
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109719/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9525594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.4.2752-2759.1998
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