RNase L Mediates the Antiviral Effect of Interferon through a Selective Reduction in Viral RNA during Encephalomyocarditis Virus Infection

The 2′,5′-oligoadenylate (2-5A) system is an RNA degradation pathway which plays an important role in the antipicornavirus effects of interferon (IFN). RNase L, the terminal component of the 2-5A system, is thought to mediate this antiviral activity through the degradation of viral RNA; however, the...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Li, Xiao-Ling, Blackford, John A., Hassel, Bret A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109719/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9525594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.4.2752-2759.1998
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