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Tolerance Induction and Autoimmune Encephalomyelitis Amelioration After Administration of Myelin Basic Protein–derived Peptide

Experimental autoimmune encephalomyelitis (EAE), a demyelinating disease of the central nervous system, is an animal model of paralyzing human disease, multiple sclerosis. EAE is readily induced by immunization with myelin basic protein (MBP) in mice transgenic for an αβ T cell receptor (TCR) that i...

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Hlavní autoři: Marusic, Suzana, Tonegawa, Susumu
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199028/
https://ncbi.nlm.nih.gov/pubmed/9254649
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