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Tolerance Induction and Autoimmune Encephalomyelitis Amelioration After Administration of Myelin Basic Protein–derived Peptide

Experimental autoimmune encephalomyelitis (EAE), a demyelinating disease of the central nervous system, is an animal model of paralyzing human disease, multiple sclerosis. EAE is readily induced by immunization with myelin basic protein (MBP) in mice transgenic for an αβ T cell receptor (TCR) that i...

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Bibliographic Details
Main Authors: Marusic, Suzana, Tonegawa, Susumu
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199028/
https://ncbi.nlm.nih.gov/pubmed/9254649
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