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Tolerance Induction and Autoimmune Encephalomyelitis Amelioration After Administration of Myelin Basic Protein–derived Peptide

Experimental autoimmune encephalomyelitis (EAE), a demyelinating disease of the central nervous system, is an animal model of paralyzing human disease, multiple sclerosis. EAE is readily induced by immunization with myelin basic protein (MBP) in mice transgenic for an αβ T cell receptor (TCR) that i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marusic, Suzana, Tonegawa, Susumu
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199028/
https://ncbi.nlm.nih.gov/pubmed/9254649
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