Correction of Population Stratification in Large Multi-Ethnic Association Studies

BACKGROUND: The vast majority of genetic risk factors for complex diseases have, taken individually, a small effect on the end phenotype. Population-based association studies therefore need very large sample sizes to detect significant differences between affected and non-affected individuals. Inclu...

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Detalhes bibliográficos
Main Authors: Serre, David, Montpetit, Alexandre, Paré, Guillaume, Engert, James C., Yusuf, Salim, Keavney, Bernard, Hudson, Thomas J., Anand, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198793/
https://ncbi.nlm.nih.gov/pubmed/18196181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001382
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