BRCA2 Variants and cardiovascular disease in a multi-ethnic study

BACKGROUND: Germline mutations of BRCA1/2 are associated with hereditary breast and ovarian cancer. Recent data suggests excess mortality in mutation carriers beyond that conferred by neoplasia, and recent in vivo and in vitro studies suggest a modulatory role for BRCA proteins in endothelial and ca...

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Detalhes bibliográficos
Main Authors: Zbuk, Kevin, Xie, Changchun, Young, Robin, Heydarpour, Mahyar, Pare, Guillaume, Davis, A Darlene, Miller, Ruby, Lanktree, Matthew B, Saleheen, Danish, Danesh, John, Yusuf, Salim, Engert, James C, Hegele, Robert A, Anand, Sonia S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464815/
https://ncbi.nlm.nih.gov/pubmed/22809218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-13-56
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