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Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

OBJECTIVE: Thiazolidinediones are used to treat type 2 diabetes. Their use has been associated with peripheral edema and congestive heart failure—outcomes that may have a genetic etiology. RESEARCH DESIGN AND METHODS: We genotyped 4,197 participants of the multiethnic DREAM (Diabetes REduction Asses...

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Detalhes bibliográficos
Main Authors: Bailey, Swneke D., Xie, Changchun, Do, Ron, Montpetit, Alexandre, Diaz, Rafael, Mohan, Viswanathan, Keavney, Bernard, Yusuf, Salim, Gerstein, Hertzel C., Engert, James C., Anand, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945168/
https://ncbi.nlm.nih.gov/pubmed/20628086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc10-0452
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