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Population pharmacokinetics and bioavailability of tacrolimus in kidney transplant patients

AIMS: The use of tacrolimus is complicated by its narrow therapeutic index and wide intra- and interpatient variability. Tacrolimus population pharmacokinetics, including bioavailability, were investigated in an adult kidney transplant cohort to identify patient characteristics that influence pharma...

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Main Authors: Antignac, Marie, Barrou, Benoit, Farinotti, Robert, Lechat, Philippe, Urien, Saïk
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198785/
https://ncbi.nlm.nih.gov/pubmed/17425625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02895.x
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