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v-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communication

The mechanism by which v-Src disrupts connexin (Cx)43 intercellular gap junctional communication (GJC) is not clear. In this study, we determined that Tyr247 (Y247) and the previously identified Tyr265 (Y265) site of Cx43 were the primary phosphorylation targets for activated Src in vitro. We establ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lin, Rui, Warn-Cramer, Bonnie J., Kurata, Wendy E., Lau, Alan F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196463/
https://ncbi.nlm.nih.gov/pubmed/11514593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200102027
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