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v-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communication

The mechanism by which v-Src disrupts connexin (Cx)43 intercellular gap junctional communication (GJC) is not clear. In this study, we determined that Tyr247 (Y247) and the previously identified Tyr265 (Y265) site of Cx43 were the primary phosphorylation targets for activated Src in vitro. We establ...

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Detalhes bibliográficos
Main Authors: Lin, Rui, Warn-Cramer, Bonnie J., Kurata, Wendy E., Lau, Alan F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196463/
https://ncbi.nlm.nih.gov/pubmed/11514593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200102027
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