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v-Src Tyrosine Phosphorylation of Connexin43: Regulation of Gap Junction Communication and Effects on Cell Transformation
The oncogenic tyrosine kinase, v-Src, phosphorylates connexin43 (Cx43) on Y247 and Y265 and inhibits Cx43 gap junctional communication (GJC), the process of intercellular exchange of ions and metabolites. To test the role of a negative charge on Cx43 induced by tyrosine phosphorylation, we expressed...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712291/ https://ncbi.nlm.nih.gov/pubmed/16916748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15419060600848516 |
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