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v-Src Tyrosine Phosphorylation of Connexin43: Regulation of Gap Junction Communication and Effects on Cell Transformation

The oncogenic tyrosine kinase, v-Src, phosphorylates connexin43 (Cx43) on Y247 and Y265 and inhibits Cx43 gap junctional communication (GJC), the process of intercellular exchange of ions and metabolites. To test the role of a negative charge on Cx43 induced by tyrosine phosphorylation, we expressed...

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Bibliografske podrobnosti
Main Authors: Lin, Rui, Martyn, Kendra D., Guyette, Carrie V., Lau, Alan F., Warn-Cramer, Bonnie J.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712291/
https://ncbi.nlm.nih.gov/pubmed/16916748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15419060600848516
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