The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein
Telomerase is a ribonucleoprotein reverse transcriptase that synthesizes telomeric DNA. A pseudoknot structure is phylogenetically conserved within the RNA component of telomerase in all ciliated protozoans examined. Here, we report that disruptions of the pseudoknot base pairing within the telomera...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1999
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21964/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10359761/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.12.6621 |
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