The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein

Telomerase is a ribonucleoprotein reverse transcriptase that synthesizes telomeric DNA. A pseudoknot structure is phylogenetically conserved within the RNA component of telomerase in all ciliated protozoans examined. Here, we report that disruptions of the pseudoknot base pairing within the telomera...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Gilley, David, Blackburn, Elizabeth H.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1999
Onderwerpen:	Biological Sciences
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21964/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10359761/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.12.6621
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