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CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding

To study the role of CD8β in T cell function, we derived a CD8α/β(−) (CD8(−/−)) T cell hybridoma of the H-2K(d)–restricted N9 cytotoxic T lymphocyte clone specific for a photoreactive derivative of the Plasmodium berghei circumsporozoite peptide PbCS 252-260. This hybridoma was transfected either wi...

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Autors principals: Renard, Valery, Romero, Pedro, Vivier, Eric, Malissen, Bernard, Luescher, Immanuel F.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196369/
https://ncbi.nlm.nih.gov/pubmed/8976201
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