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Thymus-derived Glucocorticoids Regulate Antigen-specific Positive Selection

While it is generally believed that the avidity of the T cell antigen receptor (TCR) for self antigen/major histocompatibility complex (MHC) determines a thymocyte's fate, how the cell discriminates between a stimulus that causes positive selection (survival) and one that causes negative select...

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Main Authors: Vacchio, Melanie S., Ashwell, Jonathan D.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196338/
https://ncbi.nlm.nih.gov/pubmed/9166432
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