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V(D)J Recombination: Modulation of RAG1 and RAG2 Cleavage Activity on 12/23 Substrates by Whole Cell Extract and DNA-bending Proteins

Antigen receptor gene rearrangement is directed by DNA motifs consisting of a conserved heptamer and nonamer separated by a nonconserved spacer of either 12 or 23 base pairs (12 or 23 recombination signal sequences [RSS]). V(D)J recombination requires that the rearranging DNA segments be flanked by...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sawchuk, Dennis J., Weis-Garcia, Frances, Malik, Sohail, Besmer, Eva, Bustin, Michael, Nussenzweig, Michel C., Cortes, Patricia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 1997
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196333/
https://ncbi.nlm.nih.gov/pubmed/9166431
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