Chargement en cours...

V(D)J Recombination: Modulation of RAG1 and RAG2 Cleavage Activity on 12/23 Substrates by Whole Cell Extract and DNA-bending Proteins

Antigen receptor gene rearrangement is directed by DNA motifs consisting of a conserved heptamer and nonamer separated by a nonconserved spacer of either 12 or 23 base pairs (12 or 23 recombination signal sequences [RSS]). V(D)J recombination requires that the rearranging DNA segments be flanked by...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sawchuk, Dennis J., Weis-Garcia, Frances, Malik, Sohail, Besmer, Eva, Bustin, Michael, Nussenzweig, Michel C., Cortes, Patricia
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196333/
https://ncbi.nlm.nih.gov/pubmed/9166431
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!