Patterns of Immunodominance in HIV-1–specific Cytotoxic T Lymphocyte Responses in Two Human Histocompatibility Leukocyte Antigens (HLA)-identical Siblings with HLA-A*0201 Are Influenced by Epitope Mutation

Primary human immunodeficiency virus (HIV) infection is controlled principally by HIV-specific cytotoxic T lymphocytes (CTL) to a steady-state level of virus load, which strongly influences the ultimate rate of progression to disease. Epitope selection by CTL may be an important determinant of the d...

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Autori principali: Goulder, P.J.R., Sewell, A.K., Lalloo, D.G., Price, D.A., Whelan, J.A., Evans, J., Taylor, G.P., Luzzi, G., Giangrande, P., Phillips, R.E., McMichael, A.J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1997
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196285/
https://ncbi.nlm.nih.gov/pubmed/9126923
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