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Lack of Allelic Exclusion in B Cell Chronic Lymphocytic Leukemia

We determined the immunoglobulin (Ig) V(H) subgroup expressed by the leukemia cells of 108 patients with B cell chronic lymphocytic leukemia (CLL). Surprisingly, we found that six samples (5%) each expressed Ig of more than one V(H) subgroup. Southern blot analysis demonstrated that these samples ea...

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Detalhes bibliográficos
Main Authors: Rassenti, Laura Z., Kipps, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196272/
https://ncbi.nlm.nih.gov/pubmed/9126924
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