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The Pathogenesis of Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL) is characterized by the clonal expansion of CD5(+)CD23(+) B cells in blood, marrow, and second lymphoid tissues. Gene-expression profiling and phenotypic studies suggest that CLL is probably derived from CD5(+) B cells similar to those found in the blood of healthy...

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Detalhes bibliográficos
Main Authors: Zhang, Suping, Kipps, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144790/
https://ncbi.nlm.nih.gov/pubmed/23987584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathol-020712-163955
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